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. Author manuscript; available in PMC: 2017 Feb 1.
Published in final edited form as: Mol Cancer Res. 2015 Nov 18;14(2):207–215. doi: 10.1158/1541-7786.MCR-15-0321

Figure 1.

Figure 1

(A) Each data point represents the normalized gene-level dependency scores for ABL1 calculated using ATARiS (gene solution 1) in the 30 hematopoietic and lymphoid cell lines tested (8). The three most sensitive lines (indicated by red circles) are the only lines within this data set known to harbor the BCR-ABL1 translocation.

(B) Each data point represents the normalized gene-level dependency scores for ESR1 in the 13 breast cancer cell lines tested (8). The four most sensitive lines (indicated by red circles) are the only breast lines within this data set known to be positive for the estrogen receptor.

(C) Each data point represents the normalized gene-level dependency scores for MAP2K1 in the 21 lung cancer cell lines tested (8). The most sensitive line (indicated by the red circle) is the only lung line within this data set known to harbor a MAP2K1 mutation.