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Binding Affinity Data for 8i
| Bromodomain | Kd (nM)a |
|---|---|
| TRIM24(PHD-bromo) | 1.3 |
| BRPF1 | 2.1 |
| BRPF2b | 12 |
| BRPF3 | 27 |
| BAZ2B | 400 |
| TAF1(domain 2) | 1,800 |
| BRD4(domains 1, 2) | >10,000 |
Mean of 4 determinations in bromoELECTSM recombinant protein binding assays performed at DiscoveRx (http://www.discoverx.com).
Also known as BRD1.
