Fig. 4.

Hypothesis: LPMOs (AA11) break the β-1,4-bonds between N-acetylglucosamine moieties in the glycosylation of serine and threonine in the non-coiled head structure of the keratin filaments; this leads to changes in the charge of the keratin filament head structure (and possibly also of the tail structure (Sprecher et al. 2001)); eventually this causes the de-assembly of the intermediate (self-assembled) keratin filaments. Permission for re-publishing has been received from copyright owners