Table 4.

Linear regression with % change in eGFR per year using the time-averaged dataset

CKD stage	Characteristics	β	95 % CI	Adjusted R 2	t value	p value
Total (n = 770)	TPU/CrU_t	2.77	2.22 to 3.31	0.41	10.00	<0.001
	P_t	5.35	4.02 to 6.67	0.49	7.91	<0.001
	UA_t	1.68	1.19 to 2.17	0.55	6.76	<0.001
	Hb_t	−1.49	−1.91 to −1.07	0.57	−7.03	<0.001
	Sex (M)	3.39	2.08 to 4.71	0.59	5.07	<0.001
	SBP_t	0.09	0.04 to 0.13	0.59	3.89	<0.001
	Age	−0.07	−0.11 to −0.02	0.59	−2.80	0.005
	Alb_t	−2.52	−4.38 to −0.65	0.60	−2.65	0.008
3a (n = 352)	TPU/CrU_t	1.78	1.18 to 2.38	0.34	5.85	<0.001
	UA_t	1.37	0.83 to 1.90	0.42	5.02	<0.001
	Hb_t	−1.49	−1.92 to −1.05	0.49	−6.71	<0.001
	Sex (M)	3.05	1.69 to 4.40	0.52	4.43	<0.001
	Na_t	−0.35	−0.64 to −0.06	0.53	−2.36	0.019
	Alb_t	−3.68	−5.61 to −1.75	0.54	−3.74	<0.001
	SBP_t	0.09	0.04 to 0.13	0.55	3.74	<0.001
	Age	−0.07	−0.11 to −0.02	0.56	−2.83	0.005
3b (n = 230)	TPU/CrU_t	3.32	2.68 to 3.96	0.44	10.21	<0.001
	UA_t	2.01	1.30 to 2.73	0.50	5.54	<0.001
	Hb_t	−1.11	−1.63 to −0.59	0.54	−4.18	<0.001
	P_t	2.99	0.97 to 5.00	0.56	2.93	0.004
4 (n = 188)	TPU/CrU_t	4.53	3.32 to 5.74	0.37	7.40	<0.001
	P_t	7.50	4.08 to 10.92	0.48	4.32	<0.001
	UA_t	2.53	1.19 to 3.86	0.52	3.74	<0.001
	Hb_t	−1.90	−3.13 to −0.67	0.54	−3.05	0.003
	Sex (M)	3.88	0.17 to 7.60	0.55	2.06	0.041

Independent variables included age, sex, eGFR_0, DMN, SBP_t, Hb_t, Alb_t, UA_t, Na_t, K_t, Na-Cl_t, cCa_t, P_t, CRP_t, LDL-C_t, TPU/CrU_t, UB_score_t, RASi_t