Table 7.

Multivariate logistic regression among three groups according to % change in eGFR in the time-averaged dataset (n = 770)

Reference	Group	Characteristics	β	Wald	Exp(β)	95 % CI	p value
Group 1 (n = 561)	Group 2 (n = 137)	TPU/CrU_t	0.92	59.61	2.50	1.98 to 3.16	<0.001
		Hb_t	−0.53	34.97	0.59	0.49 to 0.70	<0.001
		UA_t	0.71	32.94	2.04	1.60 to 2.60	<0.001
		Sex(M)	1.04	10.47	2.82	1.51 to 5.28	0.001
		P_t	1.03	9.60	2.79	1.46 to 5.35	0.002
		CRP_t	0.74	5.51	2.09	1.13 to 3.85	0.019
	Group 3 (n = 72)	TPU/CrU_t	1.33	74.77	3.78	2.79 to 5.10	<0.001
		Hb_t	−0.93	35.05	0.40	0.29 to 0.54	<0.001
		P_t	2.80	32.95	16.41	6.31 to 42.64	<0.001
		UA_t	0.86	19.45	2.36	1.61 to 3.45	<0.001
		Sex(M)	1.90	14.94	6.71	2.56 to 17.61	<0.001
		CRP_t	1.25	6.51	3.48	1.34 to 9.08	0.011
Group 2	Group 3	P_t	1.77	19.75	5.88	2.69 to 12.83	<0.001
		TPU/CrU_t	0.41	14.77	1.51	1.22 to 1.86	<0.001
		Hb_t	−0.40	8.09	0.67	0.51 to 0.88	0.004
		Sex(M)	0.87	4.18	2.38	1.04 to 5.46	0.041
Group 1 + 2	Group 3	TPU/CrU_t	0.58	19.84	1.78	1.38 to 2.29	<0.001
		P_t	1.87	19.47	6.49	2.83 to 14.89	<0.001
		eGFR_0	−0.05	7.67	0.95	0.92 to 0.99	0.006
		Sex(M)	1.15	7.56	3.17	1.39 to 7.21	0.006
		Alb_t	−1.33	7.02	0.26	0.10 to 0.71	0.008
		Hb_t	−0.38	6.36	0.68	0.51 to 0.92	0.012

Groups 1, 2, and 3 correspond to % decline of eGFR per year <10 %, 10–25 % and >25 %, respectively

Independent variables included age, sex, eGFR_0, DMN, SBP_t, Hb_t, Alb_t, UA_t, Na_t, K_t, Na-Cl_t, cCa_t, P_t, CRP_t, LDL-C_t, TPU/CrU_t, UB_score_t, RASi_t