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. 2016 Feb 13;3(1):ENEURO.0085-15.2016. doi: 10.1523/ENEURO.0085-15.2016

Table 1:

Model parameters

Compartment Dimensions
(length × diameter)
Segments (n) Max gNa+/gK+ (pS/µm2)
Dendrites 300 µm, tapered from 2.5 to 0.5 µm 101 Na+, linear decrease, 100-20; K+, linear decrease, 100-20
Somata 20 × 20 µm 11 Na+, 100; K+, 100
Proximal axon 0-100 × 1.5 µm ∼1/µm Na+, 100; K+, 100
AIS 5-100 × 1.5 µm ∼1/µm Na+, 8000; K+, 2000
Myelin segments (20) 100 × 1 µm 21 Passive; CM/10, RM · 10
Nodes of Ranvier (20) 1 × 1.5 µm 3 Na+, 2,667; K+, 667
Unmyelinated axon 2000 × 1 µm 401 Na+, 300; K+, 60
Axon endpoint 10 × 10 µm 11 Passive; CM · 2, RM/2
MSN, DGC, Purkinje, L5, and CA3 neurons Reconstructed morphologies ∼1/µm Somata: Na+, 100; K+, 100;
Dendrites, passive

DGC, Dentate granule cell; Epas, reversal potential for passive leak conductance; MSN, medium spiny neuron. General parameters: RM = 15 kΩ · cm2; CM = 1 µF/cm2; Ri = 100 Ω · cm; Epas = −70 mV; time steps, 0.1 or 1 µs; nominal temperature, 37°C.