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. 2016 Feb 17;6:21596. doi: 10.1038/srep21596

Figure 2. Knockdown of β-catenin suppressed metastatic potential of brain metastatic PC14PE6/LvBr4 cells.

Figure 2

(A) To evaluate the effect of β-catenin silencing on metastatic potential, brain metastatic PC14PE6/LvBr4 cells were transfected with control (CTRL) or β-catenin-specific siRNA for 48 h. The expression level of β-catenin was determined by western blotting. (B–D) Metastatic potential including invasion (B) and migration (C: Transwell, D: wound closure) was determined as described in the Materials and Methods. Data are means and standard deviation from more than three independent experiments. *p < 0.05.