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. 2016 Feb 17;6:21315. doi: 10.1038/srep21315

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(a–c): Autofluorescent structures (green fibers) and nuclei (green ovals) were unchanged after Lat-A treatment. (d–f): The F-actin cortical network in regions of the UM (d), CSM (e) and JCT (f) was disrupted leaving only punctate cytosolic collections. (g–i) (merge): cortical F-actin association with the autofluorescent structure is absent but punctate collections are prominent. (j–o): Detail of punctate perinuclear F-actin (red) in isolated cells in the absence of cortical actin in the UM (j,k), CSM (l,m) and JCT (n,o). Closed arrowheads: cortical F-actin. Open arrowheads: punctate F-actin. Green: autofluorescent structure and Hoechst-labeled nuclei. Red: F-actin.