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(a) Thiol-end modification scheme for sHA (sHA-eSH). (b) QCM-D response, i.e., changes in frequency (Δf/n, shades of blue) and dissipation (D, shades of orange) induced by grafting sHA-eSH and subsequently introducing 0.5% BSA to investigate unspecific adsorption. (c) Proposed architecture of sHA-eSH immobilized on the gold sensor surface. (B: refers to buffer, PBS).
