Table 1. Demographics, clinical characteristics and task performance of participants.
| Demographics/clinical characteristics | Patients |
||
|---|---|---|---|
| Healthy participants n = 21 (10M:11F) | Preserved WMa n = 19 (8M:11F) | Impaired WMa n = 16 (11M:5F) | |
| Mean ± SD | Mean ± SD | Mean ± SD | |
| Age (years) | 22.38 ± 3.94 | 24.84 ± 6.68 | 22.63 ± 6.71 |
| Education (years) | 13.33 ± 1.83 | 12.63 ± 2.11 | 12.19 ± 2.69 |
| WAIS-Digital | − | 70.63 ± 16.11 | 59.25 ± 12.00 |
| WAIS-Information | − | 18.82 ± 4.98 | 15.72 ± 4.03 |
| Age at illness onset (years) | − | 24.11 ± 6.63 | 22.94 ± 6.63 |
| Duration of illness (months) | − | 8.25 ± 5.69 | 8.38 ± 4.24 |
| CPZ equivalents (mg) | − | 234.22 ± 133.99 | 319.79 ± 287.02 |
| SAPS total | − | 19.95 ± 8.53 | 14.19 ± 11.98 |
| SANS total | − | 24.05 ± 24.50 | 38.44 ± 23.44 |
| WM Performances | Mean ± SD | Mean ± SD | Mean ± SD |
| 2-back target accuracy | 79.05 ± 13.07 | 75.74 ± 14.78 | 42.69 ± 18.30 |
| 2-back non-target accuracy | 90.14 ± 7.30 | 90.58 ± 8.39 | 66.88 ± 37.90 |
| 2-back target RT | 619.64 ± 125.26 | 689.87 ± 121.94 | 729.34 ± 205.07 |
| 2-back non-target RT | 631.56 ± 121.09 | 695.30 ± 128.38 | 733.02 ± 160.13 |
Note:
aDefined by performance on the 2-back memory task; WM, working memory; M, male; F, female; SD, standard deviation; WAIS-Digital, the Digit Symbol Subscale of Wechsler Adult Intelligence Scale; WAIS-Information, the information subscale of Wechsler Adult Intelligence Scale; CPZ, chlorpromazine; SAPS, Scale for Assessment of Positive Symptoms; SANS, Scale for the Assessment of Negative Symptoms, RT, response time.