Figure 7.
PET/CT images (maximum intensity projection) of Balb/C mice 24 h post injection with 64Cu-Rituximab-immunoconjugates. (A) 64Cu-Sar-CO-Rituximab and (B) 64Cu-DTPA-Rituximab given as examples of macrocycle containing immunoconjugates (A, showing predominantly blood pool activity) and ,immunoconjugates containing DTPA derivatives (B, showing predominantly liver and gut activity). Corresponding images for the other chelators tested are presented in supplementary data.