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. 2016 Feb 17;47:32. doi: 10.1186/s13567-016-0317-1

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© Müller et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Cerebral parasite load in non-pregnant and pregnant mice treated with buparvaquone. BALB/c mice were infected with Nc-Spain7 tachyzoites and subsequently treated with buparvaquone (BPQ) in corn oil or corn oil only (Placebo) as detailed in Section “Materials and methods”. Non-pregnant mice were euthanized 3 weeks pi, dams were euthanized 30 days post partum (pp), thus 44 days pi. After euthanasia, brains were collected and the amount of tachyzoites was determined by quantitative PCR and are presented as box plots (**p < 0.001; Kruskal–Wallis-test). A non pregnant mice, B dams.