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Neutralization sensitivity of transmitted/founder P08 and P11 pseudoviruses to various bnAbs
| Antibody | Epitope | IC50 (µg/ml) | |
|---|---|---|---|
| P08-gp160 | P11-gp160 | ||
| PG9 | V1V2 | 0.690 | 1.916 |
| PG16 | V1V2 | ND | ND |
| PGT121 | Glycan-V3 | ND | ND |
| PGT128 | Glycan-V3 | 0.011 | 0.015 |
| PGT135 | Glycan-V3 | ND | ND |
| 2G12 | Glycan | ND | ND |
| b12 | CD4bs | ND | ND |
| VRC01 | CD4bs | 8.306 | 6.808 |
| Ibalizumab | CD4 | 0.027 | 0.022 |
| 2F5 | MPER | 0.415 | 2.17 |
| 4E10 | MPER | 0.571 | 0.568 |
| 10E8 | MPER | 0.131 | 0.217 |
ND not detectable
