Figure 3. The SENP2 homozygous mutant exhibits extraembryonic abnormalities.
Histology examines the placentas of SENP2+/+ (A–D) and SENP2−/− (E–H) in transverse sections at E10.5. Labyrinth (L), spongiotrophoblast (S) and trophoblast giant cell (G) layers were defined by blue, red and green broken lines, respectively. Scale bars, 500 μm (A,E); 50 μm (B–D,F–H).