Table 2. Change of Clinical Characteristics after Treatment.
Baseline | 6 month | 12 month | P value(baseline-6 months) | P value(6–12 months) | P value(baseline-12 months) | |
---|---|---|---|---|---|---|
SBP (mmHg) | 157 ± 23 | 143 ± 20 | 141 ± 22 | <0.001 | 0.173 | <0.001 |
DBP (mmHg) | 92 ± 14 | 88 ± 12 | 86 ± 11 | 0.004 | 0.106 | <0.001 |
baPWV (cm/s) | 1636 ± 310 | 1533 ± 278 | 1562 ± 313 | <0.001 | 0.248 | 0.006 |
haPWV (cm/s) | 1096 ± 138 | 1048 ± 129 | 1049 ± 130 | <0.001 | 0.415 | 0.005 |
Potassium (mmol/L) | 3.5 ± 0.8 | 4.4 ± 0.5 | 4.4 ± 0.4 | <0.001 | 0.545 | <0.001 |
PAC (ng/dL) | 61 ± 40 | 28 ± 19 | 33 ± 25 | <0.001 | 0.018 | <0.001 |
PRA (ng/mL/hr) | 1.0 ± 3.1 | 3.1 ± 6.4 | 4.5 ± 10.8 | <0.001 | 0.216 | <0.001 |
Log PAC | 1.7 ± 0.3 | 1.4 ± 0.3 | 1.5 ± 0.2 | <0.001 | 0.009 | <0.001 |
Log PRA | −0.8 ± 0.8 | 0.1 ± 0.6 | 0.2 ± 0.6 | <0.001 | 0.110 | <0.001 |
Log ARR | 2.3 ± 0.9 | 1.3 ± 0.6 | 1.3 ± 0.6 | <0.001 | 0.712 | <0.001 |
Values are mean ± SD. SBP = systolic blood pressure; DBP = diastolic blood pressure; PAC = plasma aldosterone concentration; PRA = plasma renin activity; Log PAC = log-transformed plasma aldosterone concentration; Log PRA = log-transformed plasma renin activity; Log ARR = log-transformed aldosterone to renin ratio; baPWV = brachial-ankle pulse wave velocity; haPWV: = heart-ankle pulse wave velocity.