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. 2016 Feb 17;6:20862. doi: 10.1038/srep20862

Table 2. Change of Clinical Characteristics after Treatment.

  Baseline 6 month 12 month P value(baseline-6 months) P value(6–12 months) P value(baseline-12 months)
SBP (mmHg) 157 ± 23 143 ± 20 141 ± 22 <0.001 0.173 <0.001
DBP (mmHg) 92 ± 14 88 ± 12 86 ± 11 0.004 0.106 <0.001
baPWV (cm/s) 1636 ± 310 1533 ± 278 1562 ± 313 <0.001 0.248 0.006
haPWV (cm/s) 1096 ± 138 1048 ± 129 1049 ± 130 <0.001 0.415 0.005
Potassium (mmol/L) 3.5 ± 0.8 4.4 ± 0.5 4.4 ± 0.4 <0.001 0.545 <0.001
PAC (ng/dL) 61 ± 40 28 ± 19 33 ± 25 <0.001 0.018 <0.001
PRA (ng/mL/hr) 1.0 ± 3.1 3.1 ± 6.4 4.5 ± 10.8 <0.001 0.216 <0.001
Log PAC 1.7 ± 0.3 1.4 ± 0.3 1.5 ± 0.2 <0.001 0.009 <0.001
Log PRA −0.8 ± 0.8 0.1 ± 0.6 0.2 ± 0.6 <0.001 0.110 <0.001
Log ARR 2.3 ± 0.9 1.3 ± 0.6 1.3 ± 0.6 <0.001 0.712 <0.001

Values are mean ± SD. SBP = systolic blood pressure; DBP = diastolic blood pressure; PAC = plasma aldosterone concentration; PRA = plasma renin activity; Log PAC = log-transformed plasma aldosterone concentration; Log PRA = log-transformed plasma renin activity; Log ARR = log-transformed aldosterone to renin ratio; baPWV = brachial-ankle pulse wave velocity; haPWV: = heart-ankle pulse wave velocity.