Table 1.
| Property | U6 wt | Mutant 17 |
|---|---|---|
| Kd (nM) | 21 ± 9 | 2.2 ± 0.2 |
| Bmax (% bound) | 100 ± 8 | 96 ± 1 |
| Hill coefficient | 0.49 ± 0.07 | 1.3 ± 0.1 |
| koff x 10−5 (s−1) | 20 ± 2 | 4 ± 0.3 |
| Calculated kon x 103 (M−1s−1) | 9.5 | 18 |
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