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Pulse sequences for the measurement of 15N and 13C R1ρ in uniformly 13C/15N labeled nucleic acids (A) The carbon and nitrogen nuclei that are targeted in RNA for R1ρ measurements are highlighted. Pulse sequences for 1D (B) 15N (Nikolova, E. N., et al., 2012) and (C) 13C (Hansen, A. L., et al., 2009) R1ρ experiments are as shown.
