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. 2015 Nov-Dec;41(6):1116–1125. doi: 10.1590/S1677-5538.IBJU.2014.0585

Table 2. serum Chemistry.

Parameters Normal control Induction control Treatment groups
STS alone Diazoxide alone Glibenclamide alone Diazoxide +STS Glibenclamide +STS
Urea (mg/dL) 16.50±0.9 41.94±1.1* 18.76±1.2 19.55±1.3 29.93±1.2* 16.42±1.6 13.74±1.3
Creatinine (mg/ dL) 0.35±0.02 1.03±0.07* 0.38±0.02 0.35±0.06 0.58±0.02* 0.38±0.04 0.35±0.06
ALP (U/L) 57.03±2.3 115.96±2.9* 49.25±2.4 50.73±3.2 76.18±2.4* 70.14±4.2* 41.39±2.1
Calcium (mg/dL) 6.21±0.5 5.14±0.9 4.46±0.7* 3.34±0.7* 1.57±0.2* 4.31±0.7* 4.10±0.9*

Group-1 = served as normal control; Group-2 = as a stone induction control; Group-3 = was given STS; Group-4 and Group-5 = were administered diazoxide and glibenclamide respectively and Groups 6 and 7 were pretreated with diazoxide and glibenclamide respectively half an hour before administration of STS. Data of all results are presented as mean±SD (*) p<0.05, statistically different from normal controls.