Table 3. Effect of Vit E and DEX on VCL-induced changes in antioxidant status and MDA level; all data are given as Mean±SD (n=6).
GSH-px | SOD | TAC | MDA | |
---|---|---|---|---|
(U/mg protein) | (U/mg protein) | (mmoL/mg protein) | (nmoL/mg protein) | |
Control-sham | 35.00±4.60a | 700.66±15.04a | 0.51±0.013a | 1.41±0.05a |
VCL | 10.46±2.10b | 174.53±22.50b | 0.11±0.015b | 9.21±0.26b |
VCL+E | 28.22±1.35c,e | 608.45±35.61cf | 0.42±0.012c | 4.70±0.34c |
VCL+DEX | 24.22±4.06c | 546.36±40.02d | 0.37±0.010d | 4.83±0.40c |
VCL+E+DEX | 31.26±2.28a,d,e | 651.11±16.51e,f | 0.49±0.011e | 2.36±0.12d |
Note: E: vitamin E (150mg/kg), DEX: dexamethasone (0.125mg/kg), GSH-px: glutathione peroxidase, SOD: superoxide dismutase, TAC: total antioxidant capacity, MDA: malondialdehyde, VCL: varicocele.
a,b,c,d,e,f: indicate significant differences (P<0.05) between marked data in same column.