Table 1.
Demographic baselines and clinical characteristics
| Demographic Baselines | WISE (n = 332) | WTH (n = 1003) | P Value |
|---|---|---|---|
| Mean age ± SD, yr | 55.8 ± 10.3 | 53.3 ± 10.9 | 0.0002 |
| Mean BMI ± SD, kg/m2 | 29.4 ± 6.7 | 27.2±.6 | <0.0001 |
| Diabetes, % | 12.4 | 3.5 | <0.0001 |
| Hypertension, % | 49.1 | 16.1 | <0.0001 |
| Family history of IHD, n, % | 228, 68.8 | 464, 46.3 | <0.0001 |
| Mean HDL-C ± SD, mg/dl | 53.6 ± 15.4 | 51.7 ± 14.9 | 0.10 |
| Mean LDL-C ± SD, mg/dl | 126.1 ± 45.3 | 124.0 ± 32.8 | 0.47 |
| Mean SBP ± SD, mmHg | 134.1 ± 20.2 | 129.3 ± 19.7 | 0.0002 |
| Mean DBP ± SD, mmHg | 76.3 ± 10.4 | 81.4 ± 11.2 | <.0001 |
| Mean WHR ± SD | 0.78 ± 0.08 | 0.84 ± 0.11 | <.0001 |
| Smoking, % | 30.1 | 13.6 | <0.0001 |
| Nonobstructive CAD | 60.2% (<20% stenosis); 39.8% (20–49% stenosis) | NA | <0.0001 |
Continuous characteristics are presented as means ± SD; Categorical characteristics are presented as percentage.
WISE, Women's Ischemia Syndrome Evaluation Study; WTH, St. James Women Take Heart Study; BMI, body mass index; IHD, ischemic heart diseases; HDL-C, high-density lipoprotein cholesterol; LDL, low-density lipoprotein cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; WHR, waist-hip ratio; CAD, coronary artery disease. NA, not available.