Table 3.

Regulatory factors of angiogenesis

Protein
a) Angiogenic Factors
FGF-β
FGF-α
Angiogenin
Transforming growth factor-α
Transforming growth factor-β
Tumor necrosis factor-α
Vascular endothelial growth factor (VPF/VEGF)
Platelet-derived endothelial growth factor
Granulocyte colony-stimulating factor
Placental growth factor
Interleukin-8
Hepatocyte growth factor
Proliferin
Angiopoietin-1
Leptin
hCG human chorionic gonadotropin
Estrogens
b) Angiostatic factors (natural)
Angiostatin
Thrompospodin
Endostatin
Tumor necrosis factor-α
Prolactin
Thromboxane A2
c) Angiostatic factors (therapeutic)
Thalidomide
Steroids

FGF-β = basic fibroblast growth factor; FGF-α = acidic FGF; VPF = vascular permeability factor