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. 2016 Feb 17;11(2):e0149439. doi: 10.1371/journal.pone.0149439

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© 2016 Twarog et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — (A) Violin plot depicting the distributions of cytoplasmic p-H2A.X stain intensity across all cells in 32 wells containing 32 different compounds at the highest concentrations used in analysis. The distributions show high levels of inter-compound variation, suggesting the dimension could be used to distinguish compounds. (B) Violin plot depicting the distributions of the same measurements as described in (A) normalized to the background level of 488nm intensity in each well. While some small differences remain, almost all inter-well variation has been eliminated.