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. 2015 Apr;28(2):126–132. doi: 10.1177/1971400915581740

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Figure 1. — Results of voxel-based analysis of FA and L3 maps in patient group by using TBSS. Upper panel: Red shows regions where FA correlates significantly with ALSFRS score: in highlighted areas, FA is significantly lower (p < 0.05, TFCE) when ALFSRS is lower. Lower panel: Blue shows regions where L3 correlates significantly with ALSFRS score: in highlighted areas, L3 is significantly higher (p < 0.05, TFCE) when ALSFRS is lower. For each brain section Montreal Neurological Institute (MNI) coordinates are displayed. FA: fractional anisotropy; TBSS: tract-based spatial statistics; ALSFRS: Amyotrophic Lateral Sclerosis Functional Rating Scale; L3: radial diffusivity; TFCE: threshold-free cluster enhancement.