Figure 2.

Results of voxel-based analysis of FA and L1 maps in patient group by using TBSS. Upper panel: Red shows regions where FA correlates significantly with disease duration in highlighted areas, FA is significantly lower (p < 0.05, TFCE) when disease duration is higher. Lower panel: Blue shows regions where L1 correlates significantly with disease duration in highlighted areas, L1 is significantly lower (p < 0.05, TFCE) when disease duration is higher. For each brain section Montreal Neurological Institute (MNI) coordinates are displayed. FA: fractional anisotropy; TBSS: tract-based spatial statistics; L1: axial diffusivity.