Table 2.
Volumetric and morphometric analysis of the posterior cranial fossa in children with Costello syndrome.
| Patients | Control | ||
|---|---|---|---|
| Mean value | Mean value | p-value | |
| Age (months) | 31.14 | 31.75 | 0.9 |
| Volumetric analysis of the posterior cranial fossa | |||
| PCFV (mm3) | 146347.85 | 169483.87 | 0.04 |
| PCFBV (mm3) | 132623.8 | 146413.3 | 0.2 |
| PCFV/PCFBV | 1.105 | 1.193 | 0.004 |
| CV (mm3) | 108387.6 | 122693.75 | 0.09 |
| Brainstem | 24236.2 | 22623.3 | 0.3 |
| V. CSF spaces | 13724.05 | 27769.5 | 0.001 |
| Morphometric analysis of the posterior cranial fossa | |||
| Basiocciput (mm) | 15.2857 | 19.4875 | 0.007 |
| Basisphenoid (mm) | 10.6428 | 13.075 | 0.03 |
| Supraocciput (mm) | 35.4914 | 38.515 | 0.2 |
| Tentorial angle (°) | 49.1 | 36.6837 | 0.0001 |
| Foramen magnum AP (mm) | 28.6714 | 34.655 | 0.0001 |
| Foramen magnum LL (mm) | 26.4714 | 30.471 | 0.003 |
| Right exocciput (mm) | 11.114 | 15.45 | 0.0007 |
| Left exocciput (mm) | 11.114 | 15.475 | 0.0005 |
| Right condyle (mm) | 3.857 | 5.775 | 0.0005 |
| Left condyle (mm) | 3.857 | 5.775 | 0.0005 |