Table 3.

RIFLE^a) criteria for the classification of acute kidney injury

Class	GFR criteria
Risk	Plasma creatinine increase 1.5×from baseline or GFR decline >25%
Injury	Plasma creatinine increase 2×from baseline or GFR decline >50%
Failure	Plasma creatinine increase 3×from baseline or GFR decline >75% or acute plasma creatinine >4 mg/dL
Loss	Persistent acute renal failure=complete loss of kidney function requiring dialysis for >4 weeks but >3 months
End-stage	End-stage kidney disease requiring dialysis for >3 months

GFR, glomerular filtration rate.

^a)Risk, injury, failure, loss, and end-stage kidney disease risk.