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. Author manuscript; available in PMC: 2016 Jul 11.
Published in final edited form as: Nat Immunol. 2016 Jan 11;17(3):297–303. doi: 10.1038/ni.3329

Figure 2. Immunization following non-specific bystander inflammation results in diminished antigen-specific recall response.

Figure 2

(a–c) Airway response of mice challenged with intranasal OVA following OVA immunization in the context of PBS or poly(I:C) treatment (indicated by “–“ or “+”). Total Pulmonary cell counts for (a) mononuclear cells (b) eosinophils, or (c) neutrophils. Each symbol represents a single mouse. Data are representative of two independent experiments, n ≥ 4. (d) Growth of OVA-bearing A20-tGO tumor following OVA immunization in the context of PBS or poly(I:C) treatment. Thin lines represent individual mice, thick lines represent cumulative mean tumor size. Data compiled from two independent experiments, n = 11. P -values by (a–c) Student’s two-tailed t-test, or (d) Two-way ANOVA, * P <0.05. ** P <0.001.