Table 2.

In vitro antimicrobial activity of dequalinium chloride (DQC) [66, 67, 69, 74–80]

	Gram stain	MICarange (µg/ml)	MICb90 (µg/ml)
Anaerobic bacteria
Gardnerella vaginalis	−/+	2–512	256
Atopobium vaginae	−/+	<0.0625–0.5	0.5
Bacteroides spp./Prevotella spp./Porphyromonas spp.	–	8–512	256; 512
Peptostreptococci	+	1–32
Fusobacteria	–	32–64
Aerobic gram-positive bacteria
Enterococcus faecalis	+	0.2–64	64
Lactobacillus spp.	+	0.5–8	4
Staphylococcus aureus	+	0.2–8	1.28; 8
Streptococcus agalactiae (group B streptococci)	+	2–64	8; 32
Streptococcus pyogenes (group A streptococci)	+	0.25–20	2
Aerobic gram-negative bacteria
Enterobacter spp.	–	3.1–400
Escherichia coli	–	1–400	128
Klebsiella spp.	–	3.1–400
Pseudomonas spp.	–	5–400
Serratia spp.	–	3.1–400
Proteus spp.	–	20–>1024
Fungi
Candida tropicalis		0.2–50
Candida albicans		0.2–50	1; 8
Candida glabrata		0.2–256	1; 256
Candida krusei		128	128
Aspergillus spp.		1.6–6.3
Trichophyton spp.		1.56–3.12
Protozoa
Trichomonas vaginalis		28.8–400	57.6

^aMIC_range: minimum and maximum MIC values for certain species

^bMIC₉₀: MIC value at which 90 % of the strains of this species were inhibited