Table 1.

Clinical features of patients with active hepatitis C virus infection (active hepatitis C virus group) and of those in whom hepatitis C virus infection was eradicated (eradication group) n (%)

Discrete traits	Active HCV group (n = 55)	Eradication group (n = 55)	P value
Sex			0.254
Male	22 (40)	28 (51)
Female	33 (60)	27 (49)
HCV genotype			0.003
1b	48 (87)	36 (65)
2	7 (13)	19 (35)
Quantitative traits	Mean ± SD	Mean ± SD
Age (yr)	66.9 ± 11.2	64.3 ± 12.1	0.200
BMI (kg/m2)	22.5 ± 3.2	22.8 ± 3.4	0.631
AST (IU/L)	53.1 ± 27.5	24.0 ± 7.2	< 0.001
ALT (IU/L)	49.9 ± 37.1	20.0 ± 11.7	< 0.001
Total bilirubin (mg/dL)	0.8 ± 0.3	0.7 ± 0.3	0.242
γ-GTP (IU/L)	50.4 ± 64	27.1 ± 20	0.011
Albumin (g/dL)	3.9 ± 0.4	4.4 ± 0.3	< 0.001
Hb (g/dL)	13.4 ± 1.7	14.2 ± 1.5	0.010
Platelet (104/μL)	15.0 ± 6.3	20.0 ± 17.8	0.050
FBG (mg/dL)	108 ± 32	107 ± 16	0.740
HbA1c (%)	5.4 ± 0.6	6.1 ± 0.5	0.030
Lipid profiles
Total cholesterol (mg/dL)	173.6 ± 31	200.5 ± 37.8	< 0.001
Triglyceride (mg/dL)	107.5 ± 52.0	103 ± 53.1	0.712
LDL cholesterol (mg/dL)	92.1 ± 25.7	117 ± 29.9	< 0.001
HDL cholesterol (mg/dL)	59.9 ± 17.4	64.9 ± 19.0	0.159
CETP level (μg/mL)	2.84 ± 1.00	2.40 ± 0.69	0.008

There were significant differences in the proportion of patients with HCV G1b infection. There were no significant differences in BMI, FBG levels, and HbA1c levels, whereas AST, ALT, and albumin levels differed significantly. TC and LDL-C levels were significantly lower in the active infection group than in the eradication group, whereas TG and HDL-C levels were similar in the two groups. HCV: Hepatitis C virus; BMI: Body mass index; AST: Aspartate-2-oxoglutarate aminotransferase; ALT: Alanine-2-oxoglutarate aminotransferase; γ-GTP: Gamma-glutamyl transpeptidase; Hb: Hemoglobin; FBG: Fasting blood glucose; HbA1c: Glycosylated hemoglobin; LDL: Low-density lipoprotein; HDL: High-density lipoprotein; CETP: Cholesterol ester transfer protein; LDL-C: Low-density lipoprotein cholesterol.