Passive MSN electrophysiological properties. A, Voltage response of a male (left) and a female (right) MSN to a series of hyperpolarizing current injections. B, The time constant of the membrane did not differ by sex. C, Female MSNs, at first glance, appear to exhibit increased inward rectification compared with male MSNs. D–F, However, rectified range input resistance was comparable by sex (D), as was inward rectification (E) and the percentage of inward rectification (F). Therefore, the preponderance of evidence suggests that no sex difference is present. The horizontal line in B and D through F indicates the mean. The p value within each subpanel indicates statistical significance; complete statistical information is in Table 1.