Figure 4. Inhibitive effects of human fAβ(1–42) formation by curcumin, its degradation products mixture and ferulic acid, evaluated by ThT fluorescence assay.

Each volumes of ThT solution and Aβ(1–42) with PBS buffer, and curcumin or degradation products mixture of curcumin or ferulic acid were mixed in a 1:1:1 volume ratio, and then incubated at 37 °C for 6 h. The final concentrations of Aβ(1–42), ThT, curcumin, original concentration of curcumin to degrade, and ferulic acid were 20 μM.