Table 1. Putative transcription factors involved in DNA damage responses.
| Locus ID | DNA-damaging agents |
Description of the gene product | Species | Homologue | Reference | |||
|---|---|---|---|---|---|---|---|---|
| MMS | HU | BLM | CPT | |||||
| FGSG_01106 | S | S | Related to arsenite-resistance protein 2 | Human | ARS2 | 13 | ||
| FGSG_09368 | S | S | Related to C2H2 zinc finger protein | S. cerevisiae | MSN2 | 14 | ||
| FGSG_15767 | S | S | S | S | Related to zinc finger protein SFP1 | S. cerevisiae | SFP1 | 15 |
| FGSG_09565 | S | R | Probable siderophore regulation protein (GATA factor) | A. nidulans | SREA | 23 | ||
| FGSG_01182 | S | S | S | S | Conserved hypothetical protein | S. cerevisiae | DBP4 | 20 |
| FGSG_05304 | S | S | S | S | Conserved hypothetical protein | S. cerevisiae | DBP3 | 21 |
| FGSG_01488 | S | S | Conserved hypothetical protein | N/A | N/A | N/A | ||
| FGSG_06948 | S | S | Related to tetratricopeptide repeat protein tpr1 | S. cerevisiae | CTR9 | 16 | ||
| FGSG_05520 | S | S | S | S | Related to cullin homologue 4A | Human | CUL-4A | 17 |
| FGSG_07420 | S | S | S | S | Related to cephalosporin C regulator 1 (cpcR1 gene) | F. graminearum | RFX1 | 12 |
| FGSG_16982 | S | S | Related to myosin 2 | S. cerevisiae | MYO1 | 18 | ||
| FGSG_04258 | S | Probable DNA repair protein UVS-2 | S. cerevisiae | RAD18 | 19 | |||
| FGSG_01176 | S | Conserved hypothetical protein | F. graminearum | FHS1 | This study | |||
| FGSG_00404 | R | R | S | Conserved hypothetical protein | N/A | N/A | N/A | |
| FGSG_00574 | S | Related to purine utilisation positive regulator | S. cerevisiae | PPR1 | 47 | |||
| FGSG_00573 | S | Related to GAL4-like transcriptional activator | S. cerevisiae | PPR1 | 47 | |||
MMS, methyl methanesulfonate; HU, hydroxyurea; BLM, bleomycin; CPT, camptothecin; S, more sensitive than wild-type; R, more resistant than wild-type; N/A, not applicable.