Skip to main content
. 2016 Feb 18;6:20156. doi: 10.1038/srep20156

Figure 7. Inhibition of mTORC1 or its upstream all downregulated the expansion of Th17 cells.

Figure 7

(A) Histopathological and immunohistochemistry findings (HE: ×200; IHC: ×400). The tan color indicates RORγt-positive staining. The arrows indicate positive cells. (B) The protein levels of PI3K/AKT- mTORC1 pathway and RORγt in injured lungs. (C) control; L: LPS; R: rapamycin; W: wortmannin. The mice were harvested on D2. All mice were wild type, with 3~5 mice per group.