Table 2.
Comparison of clinical characteristics in females with MS between light drinkers and non-drinkers
| Light drinkers (n = 344) | Non-drinkers (n = 797) | P-value (P a-value) | |
|---|---|---|---|
| Age (years) | 54.6 ± 7.9 | 57.5 ± 8.3 | <0.001 |
| BMI (kg/m2) | 25.9 ± 3.5 | 26.4 ± 3.6 | <0.05 |
| WC (cm) | 89.1 ± 7.1 | 90.3 ± 7.2 | <0.05 |
| SBP (mmHg) | 129.7 ± 13.3 | 131.7 ± 14.4 | (NS) |
| DBP (mmHg) | 77.9 ± 9.3 | 78.0 ± 9.4 | (NS) |
| Hypertension, n (%) | 282 (82.0 %) | 655 (82.2 %) | (NS) |
| T-CHO (mg/dl) | 214.6 ± 34.8 | 211.1 ± 32.6 | (NS) |
| TG (mg/dl) | 121.5 ± 64.8 | 122.9 ± 62.0 | (NS) |
| HDL (mg/dl) | 60.2 ± 13.8 | 59.7 ± 13.8 | (NS) |
| LDL (mg/dl) | 138.0 ± 31.1 | 135.0 ± 29.6 | (NS) |
| Dyslipidemia, n (%) | 324 (99.4 %) | 742 (93.1 %) | (NS) |
| UA (mg/dl) | 4.9 ± 1.1 | 4.9 ± 1.1 | (NS) |
| FPG (mg/dl) | 106.5 ± 14.4 | 108.5 ± 20.6 | (NS) |
| HbA1c (NGSP) (%) | 5.9 ± 0.6 | 6.1 ± 0.8 | (<0.05) |
| IGT, n (%) | 261 (75.9 %) | 591 (74.2 %) | (NS) |
| ALT (IU/l) | 27.2 ± 21.4 | 27.2 ± 18.5 | (NS) |
| AST (IU/l) | 23.0 ± 9.9 | 24.0 ± 11.2 | (NS) |
| GGT (IU/l) | 32.3 ± 27.4 | 34.8 ± 32.6 | (NS) |
| FIB-4 index | 2.5 ± 0.6 | 2.7 ± 0.7 | (NS) |
| Fatty liver, n (%) | 188 (54.7 %) | 454 (57.0 %) | (NS) |
| FL with ALT elevation, n (%) | 76 (22.1 %) | 177 (22.2 %) | (NS) |
| V-type MS, n (%) | 55 (16.0 %) | 115 (14.4 %) | (NS) |
| Past history of smoking, n (%) | 49 (14.2 %) | 54 (6.8 %) | <0.001 |
Data are given as means ± standard deviation (SD), and as number (%) for categorical variables. P-value is based on the X2 test or Student’s t-test. Significant is at the 5 % level
ALT alanine aminotransferase, AST aspartate aminotransferase, BMI body mass index, DBP diastolic blood pressure, FL fatty liver, FPG fasting plasma glucose, GGT gamma-glutamyl transpeptidase, HbA1c hemoglobin A1c, HDL high density lipoprotein, IGT impaired glucose tolerance, LDL low density lipoprotein, MS metabolic syndrome, NGSP National Glycohemoglobin Standardization Program, NS not significant, SBP systolic blood pressure, T- CHO total cholesterol, TG triglyceride, UA uric acid, V-type visceral type, WC waist circumference. ALT elevation was defined as ALT level of >31 IU/l in this study. Light drinkers were subjects who drank from more than zero to less than 20 g/day of alcohol. Non-drinkers were subjects who drank 12 drinks (one drink means less 10 g) or less per year of less than 10 g/drinking day
aAdjusted for age, BMI, WC, smoking history, dyslipidemia, hypertension, and IGT