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. Author manuscript; available in PMC: 2016 Feb 18.
Published in final edited form as: Kidney Int. 2015 Apr 8;88(2):226–234. doi: 10.1038/ki.2015.115

Figure 1. Onset and Duration of Drug Induced Kidney Injury.

Figure 1

This figure conceptualizes the varying clinical presentations of drug induced nephrotoxicity drawing similarities to the KIDIGO definitions of kidney injury. Some antimicrobials can cause an acute rise in serum creatinine in relation to the start of the medication (e.g. aminoglycosides, amphotericin). Chemotherapeutic agents, such as cisplatin, cause a rise in serum creatinine that can occur beyond 7 days. Other medications have a slower onset of injury and can take months or years to be recognized clinically (e.g. tenofovir or lithium).