. 2016 Feb 18;14:10. doi: 10.1186/s12969-016-0070-z

Table 4.

Frequencies of clinical characteristics of BD in children compared to adults

	Paediatric series					Adult series
Clinical features in %	Karincaoglu [4]	Krause [37]	Koné- Paut [7]	Atmaca [35]	Koné-Paut + [13]	Alpsoy E [38]	Krause [37]
N = patients	33	19	65	110	156	661	34
Oral aphthosis	100	100	96	100	100	100	100
Genital aphthosis	82	31.6	70	83	55	58.3	88.2
Cutaneous signs		89.5	92	76			82.4
Erythema nodosum	52	36.8	40	37	22.7	44.2	26.5
Pseudo folliculitis	51	8/19	58	39	43	55.4	ND
Pathergy test +	37	41.2	-	45.5	NS	37.8	57.1
Ocular signs	35^b		60		45	29.2	Approx 50 %
Anterior uveitis		47.4		31	30.1		47.1
Posterior uveitis		42.1	36	9 %	28		8.8
Retinal vasculitis		10.5	36	9 %	16.7		8.8
Arthralgia/arthritis	40	47.4	56	22	41	33.4	17.6
Gastro intestinal	4.8	36.8	14	NS	4.49	1.6	11.7
Neurological^a	7.2^a	26.3	15	3.6^a	5^a	3^a	5.8^a
Vascular	9.6	10.5	15	3.6	15.38	4.4	26.5
Family history of BD	19	ND	15	12	24.4	ND	ND
Age first symptom (years)	12.3 (1–16)	6.9 ± 3.9	8.4 (0–16)	11.6 (1–16)	7.83 ± 4.39	ND	30.4 ± 8

^aOther than headaches ^buveitis without details + in this study patienst were classified by an international expert committee, independently of the international criteria