Skip to main content
. 2015 Oct 21;12(6):8041–8047. doi: 10.3892/mmr.2015.4459

Figure 4.

Figure 4

CLICl is involved in the regulation of SGC-7901 gastric cancer cell invasion. Cells were treated with NAC (30 mmol/l), IAA-94 (40 µmol/l) or SB203580 (10 µmol/l) for 1 h and then exposed to H-R or normoxic conditions for 24 h. A Matrigel invasion assay was performed to examine SGC-7901 gastric cancer cell invasiveness. (A) Invaded cells were fixed and stained with crystal violet and observed under a microscope (magnification, ×100). (B) Numbers of invaded ceslls were quantified under a microscope in five randomly-selected fields. Data are expressed as the relative number of invading cells compared with those under normoxic conditions and are presented as the mean ± standard deviation. **P<0.01, vs, normoxic group; ##P<0.01, vs. H-R group. N, normoxia; H-R. H-R, hypoxia-reoxygenation; IAA-94, indanyloxyacetic acid 94; NAC, N-acetyl cysteine.