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. 2015 Oct 20;12(6):7830–7836. doi: 10.3892/mmr.2015.4455

Figure 2.

Figure 2

miR-519 regulates HL60 human AML cell viability. The HL60 cells were transfected with miR-519 mimics, miR-519 inhibitors or NCs for 24, 48 and 72 h. (A) Upregulation of miR-519 expression decreased cell viability by 25 and 30%, at 48 and 72 h, respectively, whereas (B) downregulation of miR-519 expression increased cell viability in the HL60 cells by 20 and 30% at 48 and 72 h, respectively, as determined by MTT assay. The data are presented as the mean ± standard error of the mean (n=6) from independent experiments. *P<0.05 vs. NC. miR, microRNA; AML, acute myeloid leukemia; NC, negative control.