Table 2.
Age of onset of exudative age‐related macular degeneration (AMD)
| Polymorphisms | Age of Onset of Exudative AMD Years, median (range) | Mann–Whitney U test |
|---|---|---|
| IL‐8 rs4073 A→T | ||
| AA | 71.7 (55.5–84.3) | AA versus AT and TT |
| AT | 75.5 (56.1–91.2) | p = 0.009 |
| TT | 75.6 (53.1–87.6) | |
| CFH rs1061170 T→C | ||
| CC | 73.8 (53.1–91.2) | CC versus CT and TT |
| TC | 76.3 (59.4–87.6) | p = 0.016 |
| TT | 76.2 (63.9–87.0) | |
| ARMS2 rs10490924 G→T | ||
| TT | 71.3 (55.5–87.6) | TT versus TG and GG |
| GT | 76.2 (53.1–91.2) | p = 0.001 |
| GG | 75.8 (54.5–88.1) | |
| C3 rs2230199 C→G | ||
| GG | 74.7 (63.1–85.1) | CC versus CG and GG |
| CG | 74.8 (55.4–87.6) | p = 0.267 |
| CC | 75.8 (53.1–91.2) | |
| Tobacco | ||
| Current smoker | 70.1 (54.5–82.3) | Current versus never and ex‐smokers |
| Ex‐smoker | 76.5 (62.8–88.1) | |
| Never Smoker | 75.0 (53.1–91.2) | p = 0.002 |