Table 3.
Multivariate model built with the generalized linear model procedure of SPSS 22 to estimate the effects of studied variables on the age of onset of exudative AMD
| Parameter | B | SE | 95% Wald CI | Hypothesis Test | ||
|---|---|---|---|---|---|---|
| Lower | Upper | Wald chi‐square | p‐value | |||
| IL‐8 rs4073 A→T | ||||||
| AA | −2.502 | 1.1448 | −4.746 | −0.258 | 4.776 | 0.029 |
| AT or TT | Reference | |||||
| CFH rs1061170 T→C | ||||||
| CC | −2.171 | 0.8170 | −3.773 | −0.570 | 7.064 | 0.008 |
| CT or TT | Reference | |||||
| ARMS rs10490924 G→T | ||||||
| TT | −2.973 | 0.9811 | −4.896 | −1.050 | 9.181 | 0.002 |
| TG or GG | Reference | |||||
| Smoking | ||||||
| Current smoker | −3.885 | 1.0613 | −5.965 | −1.805 | 13.398 | 0.0003 |
| Non‐ or ex‐smoker | Reference | |||||
| Intercept | 2.240 | 0.5966 | 1.071 | 3.409 | 14.100 | <0.0001 |
Dependent variable: age – 75.0 years (median age of the exudative study patients).