Table 3.
Morphology at mitosis | Morphology at birth | Cell type | Process stability | Process retraction | Cell cycle | Mitotic plane angle | Trans‐location | Mitosis location | |
---|---|---|---|---|---|---|---|---|---|
Only feature | 62 | 63.9 | 49.7 | 60.3 | 51.4 | 50 | 49.5 | 51.2 | 48.3 |
Without feature | 91.4 | 92.8 | 98.4 | 93.5 | 96.8 | 98.2 | 98.6 | 98.7 | 97.2 |
Features at birth | Morphological features | Proliferative features | All/no features | |
---|---|---|---|---|
Only feature | 64 | 80.3 | 62 | 98.9 |
Without feature | 86.2 | 86.7 | 93.7 | 38.2 |
For the nine features used for clustering, the percentage of correct predictions is shown, using mother cell type and a single feature resp. all features except one. For comparison we display the prediction accuracy if only features known at birth (processes and division position), morphological features (processes at birth and at mitosis), proliferative features (cell‐cycle length, mitosis location, mitotic plane angle, cell type), or all or no features are used for prediction. Bold numbers indicate the best, italic numbers the lowest prediction result. Results are for the combined E65 and E78 dataset, using K = 6 clusters of cell types without constraints, averaged over 20 trials with random cluster initializations. All features have similar influence on the prediction accuracy, with values around or over 50%. Morphological features are the best predictors, yielding accuracies over 62%. The combination of features allows for prediction of the daughter cell type with more than 90% accuracy (98.9% if all features are used).