Figure 3. Effects of Antibody on DENV Uptake in a Monocytic Cell Line.
(A) Enhanced virus infection in THP-1.2S cells with addition of either chimeric 4G2 or Ab513.
(B) Analysis of Ab513 and DENV localization in THP-1.2S cells. The late endosomal and lysosomal compartments of cells were stained by LAMP-1.
(C) Analysis identical to (B) except chimeric 4G2 is used as antibody.