Table 1. Quartiles of total leukocytes and diabetes mellitus risk factors of participants in MDC (n = 26 667) and MDC-CV (n = 5 473).
| MDC (N = 26 667) | |||||
| Sex-specific quartiles | Q1 | Q2 | Q3 | Q4 | p |
| N (men/women) | 2575/4246 | 2548/4097 | 2712/3790 | 2529/4170 | |
| Leukocyte count, Men median (P25—P75), (109/L) | 4.70(4.20–5.20) | 5.60(5.40–5.90) | 6.60(6.40–6.90) | 8.30(7.60–9.10) | |
| Leukocyte count, Women median (P25—P75) (109/L) | 4.70(4.0–5.00) | 5.70(5.40–5.90) | 6.70(6.50–7.00) | 8.30(7.70–9.10) | |
| Sociodemographic variables | |||||
| Age (years) | 57.6±7.0 | 58.4±7.7 | 58.4±7.7 | 57.8±8.0 | <0.001 |
| Married (%) | 68.9 | 66.3 | 66.1 | 59.8 | <0.001 |
| Low education (%) | 37.8 | 41.0 | 42.3 | 45.6 | <0.001 |
| Anthropometric measurements | |||||
| Waist circumference (cm) | 81.6±15.3 | 83.5±12.6 | 85.0±16.0 | 85.0±13.2 | <0.001 |
| BMI (kg/m2) | 25.0±3.5 | 25.7±3.8 | 25.9±4.0 | 26.0±4.2 | <0.001 |
| Medical history variables | |||||
| Family history of diabetes, (%) | 2.0 | 2.0 | 1.8 | 1.7 | 0.226 |
| Prevalent cardiovascular disease (%) | 1.7 | 2.4 | 3.2 | 3.6 | <0.001 |
| Systolic blood pressure (mmHg) | 138±19 | 141±20 | 142±20 | 143±20 | <0.001 |
| Antihypertensive medication (%) | 12.2 | 15.8 | 18.4 | 21.3 | <0.001 |
| Lipid-lowing medication (%) | 2.1 | 2.9 | 3.1 | 3.2 | <0.001 |
| Lifestyle variables | |||||
| Current smoker (%) | 13.1 | 19.6 | 30.0 | 51.2 | <0.001 |
| Low physical activity (%) | 20.8 | 22.5 | 24.3 | 28.5 | <0.001 |
| MDC-CV Subcohort (n = 5 473) | |||||
| N (men/women) | 508/768 | 643/883 | 508/762 | 586/815 | |
| Leukocyte count, median, (men/women) (109/L) | 4.30/4.30 | 5.40/5.40 | 6.40/6.40 | 7.90/7.80 | |
| Glucose (mmol/L) (n = 5082) | 4.87±0.55 | 5.01±0.85 | 5.02±0.71 | 5.07±0.80 | <0.001 |
| HbA1c (%) (n = 5082) | 4.70±0.40 | 4.79±0.49 | 4.84±0.51 | 4.97±0.55 | <0.001 |
| Insulin* (mIU/l) (n = 4912) | 6.00(4.00–8.00) | 7.00(4.00–9.00) | 7.00(5.00–10.00) | 7.00(4.75–10.00) | <0.001 |
| CRP* (mg/L) (n = 4904) | 0.90(0.50–1.80) | 1.30(0.70–2.50) | 1.50(0.80–3.10) | 2.20(1.00–4.30) | <0.001 |
All values are mean±SD, unless otherwise stated.
*insulin, CRP is presented as median and interquartile limits, due to skewed distribution. P value for log-transform value.
MDC, Malmö Diet and Cancer.