Table 4.

AnalysisofjointinfluenceofgenotypesathOGG1rs1052133 and hMUTYH rs3219472 on risk of nasopharyngeal carcinoma

Genotype		NPC	Control	P*	Adjusted ORa (95% CI)
rs1052133	rs3219472
CC	AA	13	6	1.00	1.00
GG	GG	62	83	0.043	2.887 (1.033–8.072)
GG	GA	70	101	0.026	3.183 (1.147–8.835)
GG	AA	19	27	0.040	3.392 (1.059–10.870)
CC	GG	34	37	0.111	NS
CC	GA	34	42	0.065 NS	NS
CG	GG	119	126	0.096 NS	NS
CG	AA	31	39	0.062 NS	NS
CG	GA	106	112	0.098 NS	NS
Total		488	573

Notes:

^aCalculated by multiple logistic regression after controlling for age, sex, and smoking history.

^*Calculated using the chi-squared test with respect to the P-value associated with the combination of genotype CC at hOGG1 rs1052133 and genotype AA at hMUTYH rs3219472. NS means not shown due to P>0.05.

Abbreviations: hOGG1, human 8-oxoguanine DNA glycosylase 1; hMUTYH, human MutY glycosylase homologue; NPC, nasopharyngeal carcinoma; OR, odds ratio; CI, confidence interval.