Immunologic gene expression was measured by hybridization using Nanostring (nCounter) technology in (A) gastric and (B) pulmonary tissues at 1, 3, and 6 months after colonization in Cohort 1 mice. Heat maps show expression levels of genes significantly different (FDR-adjusted p-value <0.05, t-test) at all three time points for the stomach and at 2 time points for the lung. (C) Gastric canonical pathways, significantly induced or repressed by H. pylori-infection. (D–F) Relative expression levels (normalized counts) for genes significantly different in ≥ 2 time points in each tissue. False-discovery rate adjusted p-values: *p<0.05, **p<0.01, ***p<0.001, t-test. See also Figure S3.