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. Author manuscript; available in PMC: 2016 Mar 9.
Published in final edited form as: Cell Rep. 2016 Feb 4;14(6):1395–1407. doi: 10.1016/j.celrep.2016.01.017

Figure 5. The effect of H. pylori colonization on gastric microbial community structure.

Figure 5

Principal coordinates analysis (PCoA) of the unweighted UniFrac distances computed from 16S rRNA sequences from gastric samples at an even sampling (500) depth. (A) Comparison of Cohort 1 (infected at 4-weeks) and Cohort 2 (infected at 6 weeks); combined, and separated by control or infected status, respectively. Right panel shows average unweighted UniFrac distances (+/− SEM) comparing intragroup variation for the early or late cohort to the intergroup variation (early vs late), for all mice, control mice, and infected mice. ***indicates that intragroup distance is significantly different from the intergroup distance, p<0.005, t-test. (B) Cohort 1 and Cohort 2, viewed separately, over time (month 1, 2, 3 and 6). Each gastric sample is represented as a colored circle; p-values (ADONIS test) are based on unweighted UniFrac distances Significance: p-values < 0.05. See also Figure S6 and Table S5.