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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Neurobiol Dis. 2016 Jan 4;88:29–43. doi: 10.1016/j.nbd.2015.12.019

Figure 5. Evoked field response is not altered by hypoxia and/or systemic inflammation.

Figure 5

A) Example traces of the evoked field potentials recorded by 5 electrodes in the layers 2/3 and 4 surrounding the electrically stimulated electrode in layer 4 (2 V, channel without recording trace) for each age and treatment condition (SHAM, dark grey; HYPO, blue; INFL, red; HYPO+INFL, green) in ACSF with 3 mM KCl. The field potentials marked by a colored square, corresponding to the layer 2/3 of the stimulated column, were used to calculate the input-output curves. B) Input-output curves plotted for all four treatments and all three age groups. Slices were stimulated with a monopolar biphasic stimulus in layer 4 varying between 250 mV and 4 V. The half maximum voltage was similar for all condition in each age group. C) Amplitude of the evoked field potentials for each age group and each condition in 3 mM KCl-ACSF (open boxes), 8 mM KCl-ACSF (light filled boxes) and 8 mM KCl-ACSF + 50 μM APV (dark filled boxes). Dunns test: **, p<0.01; *, p<0.05.