Table 3.
Single nucleotide polymorphisms (SNPs) and summary p-values for association tests between caries experience and genetic variants in the two studied samples.
Minor Allele Frequency | Summary p-value |
||||||
---|---|---|---|---|---|---|---|
Gene | Marker | Alleles | Turkey | Brazil | Permanent Teeth |
Primary Teeth |
|
Black | White | ||||||
TUFT1 | rs7526319 | CT | 0.338 | 0.481 | 0.469 | NS | NS |
rs4970957 | AG | 0.241 | 0.133 | 0.152 | NS | 0.009a | |
rs3828054 | AG | 0.105 | 0.448 | 0.393 | NS | NS | |
rs3790506 | AG | 0.249 | 0.4 | 0.357 | NS | NS | |
rs2337360 | AG | 0.25 | 0.366 | 0.414 | NS | NS | |
AMBN | rs4694075 | CT | 0.478 | 0.264 | 0.424 | 0.004b | NS |
rs34538475 | GT | 0.187 | 0.255 | 0.387 | NS | NS | |
ENAM | rs12640848 | AG | 0.357 | 0.451 | 0.471 | 0.06a | NS |
rs3796704 | AG | 0.12 | 0.173 | 0.133 | NS | NS | |
MMP20 | rs1784418 | CT | 0.407 | 0.388 | 0.414 | NS | NS |
TFIP11 | rs5997096 | CT | 0.47 | 0.416 | 0.444 | 0.006a | NS |
rs134136 | CT | 0.335 | 0.258 | 0.291 | 0.002a | NS | |
AMELX | rs17878486 | CT | 0.111 | 0.148 | 0.136 | 0.03a | NS |
rs946252 | AG | 0.3 | 0.183 | 0.2 | 0.025a | NS |
NS = not statistically significant.
Fisher’s exact test on the distribution of alleles.
Genotypic 2-degree of freedom test.