Table 6.
Summary of the positive associations of the genotype and allele frequency comparisons of enamel microhardness assessments in the permanent teeth after fluoride exposure.
| Gene | SNP | Above the Mean Enamel Microhardness Enamel [N(%)] |
Below the Mean Enamel Microhardness Enamel [N(%)] |
p-value | ||||
|---|---|---|---|---|---|---|---|---|
| TUFT1 | rs2337360 | Lingual/Palatine | ||||||
| Genotype | AA | 10(20.8) | 4(7.6) | 0.03 | ||||
| AG | 20(41.6) | 34(65.3) | ||||||
| GG | 18(37.5) | 14(26.9) | ||||||
| Allele | A | 40(41.6) | 42(40.3) | 0.85 | ||||
| G | 56(58.3) | 62(59.6) | ||||||
| AMBN | rs4694075 | Distal | ||||||
| Genotype | TT | 4(10.2) | 4(7.5) | 0.01 | ||||
| CT | 24(61.5) | 18(33.9) | ||||||
| CC | 11(28.2) | 31(58.4) | ||||||
| Allele | T | 32(41.02) | 26(24.5) | 0.01 | ||||
| C | 46(58.9) | 80(75.4) | ||||||
| MMP20 | rs1784418 | Mesial | ||||||
| Genotype | CC | 10(21.7) | 7(12.9) | 0.04 | ||||
| CT | 22(47.8) | 39(72.2) | ||||||
| TT | 14(30.4) | 8(14.8) | ||||||
| Allele | C | 42(45.6) | 53(49.07) | 0.62 | ||||
| T | 50(54.3) | 55(50.9) | ||||||
| C | 66(78.5) | 61(64.8) | ||||||
| TFIP11 | rs5997096 | Mesial | ||||||
| Genotype | CC | 16(37.2) | 8(18.1) | 0.06 | ||||
| CT | 19(44.1) | 20(45.4) | ||||||
| TT | 8(18.6) | 16(36.3) | ||||||
| Allele | C | 51(59.3) | 36(40.9) | 0.01 | ||||
| T | 35(40.6) | 52(59.09) | ||||||
| rs134136 | Mesial | |||||||
| Genotype | TT | 3(6.5) | 8(14.8) | 0.03 | ||||
| CT | 16(34.7) | 28(51.8) | ||||||
| CC | 27(58.6) | 18(33.3) | ||||||
| Allele | T | 22(23.9) | 44(40.7) | 0.01 | ||||
| C | 70(76.08) | 64(59.2) | ||||||
Bold indicates statistically significant differences.