Table 5.
Comparison between human blood T1 measured in vivo and blood T1 calculated by our model.
| B0 | Hct | Exp. T1 (ms) | Cal. T1 (ms) | ||
|---|---|---|---|---|---|
| Adult (20) | Arterial | 1.5T | 0.47+/−0.03 | 1499+/−74 | 1439 |
| Adult Male(25) | Venous | 1.5T | 1429+/−21 | 1229–1387 | |
| Adult Female(25) | Venous | 1.5T | 1531+/−29 | 1317–1462 | |
| Adult (20) | Arterial | 3T | 0.47+/−0.03 | 1779+/−80 | 1849 |
| Adult (20) | Venous | 3T | 0.47+/−0.03 | 1694+/−77 | 1668 |
| Adult Male (24) | Venous | 3T | 1677+/−120 | 1597–1743 | |
| Adult Female (24) | Venous | 3T | 1769+/−100 | 1680–1809 | |
| Adult Male (25) | Venous | 3T | 1618+/−30 | 1597–1743 | |
| Adult Female (25) | Venous | 3T | 1681+/−87 | 1680–1809 | |
| Adult (18) | Venous | 3T | 1825+/−104 | 1597–1809 | |
| Neonate (22) | Venous | 3T | 0.423 | 1757 | 1726 |
| Sickle Cell Patient | Venous | 3T | 0.233+/−0.039 | 1910+/−89 | 1990 |
| Female (18) | |||||
| Sickle Cell Patient | Venous | 3T | 0.235+/−0.029 | 1938+/−82 | 1987 |
| Male (18) | |||||
| Adult Male (25) | Venous | 7T | 2012+/−119 | 1945–2116 | |
| Adult Female (25) | Venous | 7T | 2163+/−94 | 2043–2193 | |
| Adult (29) | Venous | 7T | 2587+−283 | 1945–2193 |
In the calculation, all relaxivities and R1saline were obtained from Table 1. fMetHb was set as the average value 0.004 (73) in normal adult blood. The oxygenation fraction Y was 1.0 for arterial blood and 0.65 for venous blood, based on published range of 0.55 – 0.75 (74,75). If Hct is not specified, T1 range was calculated according to the physiological range of 0.41 – 0.53 for male and 0.36 – 0.46 for female (71).